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Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection
T cell expansion and memory formation are generally more effective when elicited by live organisms than by inactivated vaccines. Elucidation of the underlying mechanisms is important for vaccination and therapeutic strategies. We show that the massive expansion of antigen-specific CD8 T cells that o...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212878/ https://www.ncbi.nlm.nih.gov/pubmed/16129706 http://dx.doi.org/10.1084/jem.20050821 |