Cargando…

Defective Fas expression exacerbates neurotoxicity in a model of Parkinson's disease

Fas (CD95), a member of the tumor necrosis factor-receptor superfamily, has been studied extensively as a death-inducing receptor in the immune system. However, Fas is also widely expressed in a number of other tissues, including in neurons. Here, we report that defects in the Fas/Fas ligand system...

Descripción completa

Detalles Bibliográficos
Autores principales: Landau, Anne M., Luk, Kelvin C., Jones, Michelle-Lee, Siegrist-Johnstone, Rosmarie, Young, Yoon Kow, Kouassi, Edouard, Rymar, Vladimir V., Dagher, Alain, Sadikot, Abbas F., Desbarats, Julie
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212882/
https://www.ncbi.nlm.nih.gov/pubmed/16129703
http://dx.doi.org/10.1084/jem.20050163