Cargando…

Defective Fas expression exacerbates neurotoxicity in a model of Parkinson's disease

Fas (CD95), a member of the tumor necrosis factor-receptor superfamily, has been studied extensively as a death-inducing receptor in the immune system. However, Fas is also widely expressed in a number of other tissues, including in neurons. Here, we report that defects in the Fas/Fas ligand system...

Descripción completa

Detalles Bibliográficos
Autores principales:	Landau, Anne M., Luk, Kelvin C., Jones, Michelle-Lee, Siegrist-Johnstone, Rosmarie, Young, Yoon Kow, Kouassi, Edouard, Rymar, Vladimir V., Dagher, Alain, Sadikot, Abbas F., Desbarats, Julie
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2005
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212882/ https://www.ncbi.nlm.nih.gov/pubmed/16129703 http://dx.doi.org/10.1084/jem.20050163

Ejemplares similares

Differential Induction of Apoptosis by Fas–Fas Ligand Interactions in Human Monocytes and Macrophages
por: Kiener, Peter A., et al.
Publicado: (1997)

Membrane Fas Ligand Kills Human Peripheral Blood T Lymphocytes, and Soluble Fas Ligand Blocks the Killing
por: Suda, Takashi, et al.
Publicado: (1997)

Development of Inflammatory Angiogenesis by Local Stimulation of Fas In Vivo
por: Biancone, Luigi, et al.
Publicado: (1997)

Requirement of Fas for the Development of Autoimmune Diabetes in Nonobese Diabetic Mice
por: Itoh, Naoto, et al.
Publicado: (1997)

T Cell Receptor Signals Enhance Susceptibility to Fas-mediated Apoptosis
por: Wong, Brian, et al.
Publicado: (1997)

Identification of Amino Acid Residues Important for Ligand Binding to Fas
por: Starling, Gary C., et al.
Publicado: (1997)

CD40 Activation Induces Apoptosis in Cultured Human Hepatocytes via Induction of Cell Surface Fas Ligand Expression and Amplifies Fas-mediated Hepatocyte Death during Allograft Rejection
por: Afford, Simon C., et al.
Publicado: (1999)

Maximal Proliferation of Cytotoxic T Lymphocytes Requires Reverse Signaling through Fas Ligand
por: Suzuki, Ivy, et al.
Publicado: (1998)

The netrin‐1 receptor DCC promotes the survival of a subpopulation of midbrain dopaminergic neurons: Relevance for ageing and Parkinson’s disease
por: Lo, Pik‐Shan, et al.
Publicado: (2022)

Prevention of Hepatocellular Carcinoma Development Associated with Chronic Hepatitis by Anti-Fas Ligand Antibody Therapy
por: Nakamoto, Yasunari, et al.
Publicado: (2002)

B cells drive lymphocyte activation and expansion in mice with the CD45 wedge mutation and Fas deficiency
por: Gupta, Vikas A., et al.
Publicado: (2008)

FAS Engagement Induces the Maturation of Dendritic Cells (Dcs), the Release of Interleukin (Il)-1β, and the Production of Interferon γ in the Absence of IL-12 during Dc–T Cell Cognate Interaction: A New Role for FAS Ligand in Inflammatory Responses
por: Rescigno, Maria, et al.
Publicado: (2000)

Impaired TrkB Signaling Underlies Reduced BDNF-Mediated Trophic Support of Striatal Neurons in the R6/2 Mouse Model of Huntington’s Disease
por: Nguyen, Khanh Q., et al.
Publicado: (2016)

Ionizing Radiation and Chemotherapeutic Drugs Induce Apoptosis in Lymphocytes in the Absence of FAS or Fadd/Mort1 Signaling: Implications for Cancer Therapy
por: Newton, Kim, et al.
Publicado: (2000)

Natural Killer (NK) Cell–mediated Cytotoxicity: Differential Use of TRAIL and Fas Ligand by Immature and Mature Primary Human NK Cells
por: Zamai, Loris, et al.
Publicado: (1998)

Activation and Differentiation of Autoreactive B-1 Cells by Interleukin 10 Induce Autoimmune Hemolytic Anemia in Fas-deficient Antierythrocyte Immunoglobulin Transgenic Mice
por: Watanabe, Norihiko, et al.
Publicado: (2002)

The Peripheral Deletion of Autoreactive CD8(+) T Cells Induced by Cross-presentation of Self-antigens Involves Signaling through CD95 (Fas, Apo-1)
por: Kurts, Christian, et al.
Publicado: (1998)

A Critical Role for the RelA Subunit of Nuclear Factor κB in Regulation of Multiple Immune-response Genes and in Fas-induced Cell Death
por: Ouaaz, Fateh, et al.
Publicado: (1999)

Thalamostriatal degeneration contributes to dystonia and cholinergic interneuron dysfunction in a mouse model of Huntington’s disease
por: Crevier-Sorbo, Gabriel, et al.
Publicado: (2020)

Essential Lymphocyte Function Associated 1 (LFA-1): Intercellular Adhesion Molecule Interactions for T Cell–mediated B Cell Apoptosis by Fas/APO-1/CD95
por: Wang, Jin, et al.
Publicado: (1997)

Interferon γ Is Required for Activation-induced Death of T Lymphocytes
por: Refaeli, Yosef, et al.
Publicado: (2002)

Unique Chemotactic Response Profile and Specific Expression of Chemokine Receptors Ccr4 and Ccr8 by Cd4(+)Cd25(+) Regulatory T Cells
por: Iellem, Andrea, et al.
Publicado: (2001)

A standardized accelerometry method for characterizing tremor: Application and validation in an ageing population with postural and action tremor
por: Gauthier-Lafreniere, Etienne, et al.
Publicado: (2022)

Inflammatory Cytokine Profiles During Exercise in Obese, Diabetic, and Healthy Children
por: Galassetti, Pietro R., et al.
Publicado: (2011)

Complementary and Alternative Medicine in Children with Type 1 Diabetes Mellitus
por: Haliloglu, Belma, et al.
Publicado: (2011)

3M Syndrome: A Report of Four Cases in Two Families
por: Güven, Ayla, et al.
Publicado: (2011)

Quantum dot-induced cell death involves Fas upregulation and lipid peroxidation in human neuroblastoma cells
por: Choi, Angela O, et al.
Publicado: (2007)

Chronic TREM2 activation exacerbates Aβ-associated tau seeding and spreading
por: Jain, Nimansha, et al.
Publicado: (2022)

Spontaneous Development of Plasmacytoid Tumors in Mice with Defective Fas–Fas Ligand Interactions
por: Davidson, Wendy F., et al.
Publicado: (1998)

Hematopoietic-specific heterozygous loss of Dnmt3a exacerbates colitis-associated colon cancer
por: Feng, Yang, et al.
Publicado: (2023)

Defective NKT cell development in mice and humans lacking the adapter SAP, the X-linked lymphoproliferative syndrome gene product
por: Pasquier, Benoit, et al.
Publicado: (2005)

Chronic Systemic Inflammation Exacerbates Neurotoxicity in a Parkinson's Disease Model
por: Ugalde-Muñiz, Perla, et al.
Publicado: (2020)

Differential Expression of Chemokine Receptors and Chemotactic Responsiveness of Type 1 T Helper Cells (Th1s) and Th2s
por: Bonecchi, Raffaella, et al.
Publicado: (1998)

Failure to Suppress the Expansion of the Activated Cd4 T Cell Population in Interferon γ–Deficient Mice Leads to Exacerbation of Experimental Autoimmune Encephalomyelitis
por: Chu, Cong-Qiu, et al.
Publicado: (2000)

Creation of Computerized 3D MRI-Integrated Atlases of the Human Basal Ganglia and Thalamus
por: Sadikot, Abbas F., et al.
Publicado: (2011)

Defects in Macrophage Recruitment and Host Defense in Mice Lacking the CCR2 Chemokine Receptor
por: Kurihara, Takao, et al.
Publicado: (1997)

A defect in COPI-mediated transport of STING causes immune dysregulation in COPA syndrome
por: Deng, Zimu, et al.
Publicado: (2020)

Class switching and meiotic defects in mice lacking the E3 ubiquitin ligase RNF8
por: Santos, Margarida Almeida, et al.
Publicado: (2010)

NCKAP1L defects lead to a novel syndrome combining immunodeficiency, lymphoproliferation, and hyperinflammation
por: Castro, Carla Noemi, et al.
Publicado: (2020)

Inherited SLP76 deficiency in humans causes severe combined immunodeficiency, neutrophil and platelet defects
por: Lev, Atar, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_6rt1ncekr34vlarb9drmjmvdp1