Notch1 modulates timing of G(1)-S progression by inducing SKP2 transcription and p27(Kip1) degradation

Cyclin-dependent kinase inhibitors (CKIs) and Notch receptor activation have been shown to influence adult stem cells and progenitors by altering stem cell self-renewal and proliferation. Yet, no interaction between these molecular pathways has been defined. Here we show that ligand-independent and...

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Detalles Bibliográficos
Autores principales: Sarmento, Leonor M., Huang, Hui, Limon, Ana, Gordon, William, Fernandes, Jacquenilson, Tavares, Maria J., Miele, Lucio, Cardoso, Angelo A., Classon, Marie, Carlesso, Nadia
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212905/
https://www.ncbi.nlm.nih.gov/pubmed/15998794
http://dx.doi.org/10.1084/jem.20050559

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212905/
https://www.ncbi.nlm.nih.gov/pubmed/15998794
http://dx.doi.org/10.1084/jem.20050559

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