Selective activation of STAT5 unveils its role in stem cell self-renewal in normal and leukemic hematopoiesis

Although the concept of a leukemic stem cell system has recently been well accepted, its nature and the underlying molecular mechanisms remain obscure. Constitutive activation of signal transducers and activators of transcription 3 (STAT3) and STAT5 is frequently detected in various hematopoietic tu...

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Detalles Bibliográficos
Autores principales: Kato, Yuko, Iwama, Atsushi, Tadokoro, Yuko, Shimoda, Kazuya, Minoguchi, Mayu, Akira, Shizuo, Tanaka, Minoru, Miyajima, Atsushi, Kitamura, Toshio, Nakauchi, Hiromitsu
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212906/
https://www.ncbi.nlm.nih.gov/pubmed/15998795
http://dx.doi.org/10.1084/jem.20042541

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212906/
https://www.ncbi.nlm.nih.gov/pubmed/15998795
http://dx.doi.org/10.1084/jem.20042541

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