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Selective activation of STAT5 unveils its role in stem cell self-renewal in normal and leukemic hematopoiesis
Although the concept of a leukemic stem cell system has recently been well accepted, its nature and the underlying molecular mechanisms remain obscure. Constitutive activation of signal transducers and activators of transcription 3 (STAT3) and STAT5 is frequently detected in various hematopoietic tu...
| Autores principales: | , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212906/ https://www.ncbi.nlm.nih.gov/pubmed/15998795 http://dx.doi.org/10.1084/jem.20042541 |