Promiscuous gene expression in thymic epithelial cells is regulated at multiple levels

The role of central tolerance induction has recently been revised after the discovery of promiscuous expression of tissue-restricted self-antigens in the thymus. The extent of tissue representation afforded by this mechanism and its cellular and molecular regulation are barely defined. Here we show...

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Detalles Bibliográficos
Autores principales: Derbinski, Jens, Gäbler, Jana, Brors, Benedikt, Tierling, Sascha, Jonnakuty, Sunitha, Hergenhahn, Manfred, Peltonen, Leena, Walter, Jörn, Kyewski, Bruno
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212909/
https://www.ncbi.nlm.nih.gov/pubmed/15983066
http://dx.doi.org/10.1084/jem.20050471

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212909/
https://www.ncbi.nlm.nih.gov/pubmed/15983066
http://dx.doi.org/10.1084/jem.20050471

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