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Induction of vascular leakage through release of bradykinin and a novel kinin by cysteine proteinases from Staphylococcus aureus

Staphylococcus aureus is a major pathogen of gram-positive septic shock and frequently is associated with consumption of plasma kininogen. We examined the vascular leakage (VL) activity of two cysteine proteinases that are secreted by S. aureus. Proteolytically active staphopain A (ScpA) induced VL...

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Detalles Bibliográficos
Autores principales: Imamura, Takahisa, Tanase, Sumio, Szmyd, Grzegorz, Kozik, Andrzej, Travis, James, Potempa, Jan
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212919/
https://www.ncbi.nlm.nih.gov/pubmed/15897280
http://dx.doi.org/10.1084/jem.20042041