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Independent roles for IL-2 and GATA-3 in stimulating naive CD4(+) T cells to generate a Th2-inducing cytokine environment
T cell receptor (TCR) signaling plays an important role in early interleukin (IL)-4 production by naive CD4(+) T cells. This “antigen-stimulated” early IL-4 is sufficient for in vitro Th2 differentiation. Here, we provide evidence that early IL-4 production by naive CD4(+) T cells stimulated with co...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212937/ https://www.ncbi.nlm.nih.gov/pubmed/16172258 http://dx.doi.org/10.1084/jem.20051304 |