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Low-dose irradiation promotes tissue revascularization through VEGF release from mast cells and MMP-9–mediated progenitor cell mobilization

Mast cells accumulate in tissues undergoing angiogenesis during tumor growth, wound healing, and tissue repair. Mast cells can secrete angiogenic factors such as vascular endothelial growth factor (VEGF). Ionizing irradiation has also been shown to have angiogenic potential in malignant and nonmalig...

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Detalles Bibliográficos
Autores principales: Heissig, Beate, Rafii, Shahin, Akiyama, Haruyo, Ohki, Yuichi, Sato, Yayoi, Rafael, Tejada, Zhu, Zhenping, Hicklin, Daniel J., Okumura, Ko, Ogawa, Hideoki, Werb, Zena, Hattori, Koichi
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212942/
https://www.ncbi.nlm.nih.gov/pubmed/16157686
http://dx.doi.org/10.1084/jem.20050959