Modifier loci condition autoimmunity provoked by Aire deficiency

Loss of function mutations in the autoimmune regulator (Aire) gene in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy patients and mutant mice lead to autoimmune manifestations that segregate as a monogenic trait, but with wide variation in the spectrum of organs targeted. To investig...

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Detalles Bibliográficos
Autores principales: Jiang, Wenyu, Anderson, Mark S., Bronson, Roderick, Mathis, Diane, Benoist, Christophe
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212943/
https://www.ncbi.nlm.nih.gov/pubmed/16172259
http://dx.doi.org/10.1084/jem.20050693

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212943/
https://www.ncbi.nlm.nih.gov/pubmed/16172259
http://dx.doi.org/10.1084/jem.20050693

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