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Cytosolic phospholipase A(2)α–deficient mice are resistant to experimental autoimmune encephalomyelitis
Experimental autoimmune encephalomyelitis (EAE), a Th1-mediated inflammatory disease of the central nervous system (CNS), is a model of human multiple sclerosis. Cytosolic phospholipase A(2) α (cPLA(2) α), which initiates production of prostaglandins, leukotrienes, and platelet-activating factor, is...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212947/ https://www.ncbi.nlm.nih.gov/pubmed/16172261 http://dx.doi.org/10.1084/jem.20050665 |