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Cytosolic phospholipase A(2)α–deficient mice are resistant to experimental autoimmune encephalomyelitis

Experimental autoimmune encephalomyelitis (EAE), a Th1-mediated inflammatory disease of the central nervous system (CNS), is a model of human multiple sclerosis. Cytosolic phospholipase A(2) α (cPLA(2) α), which initiates production of prostaglandins, leukotrienes, and platelet-activating factor, is...

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Detalles Bibliográficos
Autores principales: Marusic, Suzana, Leach, Michael W., Pelker, Jeffrey W., Azoitei, Mihai L., Uozumi, Naonori, Cui, Junqing, Shen, Marina W.H., DeClercq, Charlene M., Miyashiro, Joy S., Carito, Brenda A., Thakker, Paresh, Simmons, David L., Leonard, John P., Shimizu, Takao, Clark, James D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212947/
https://www.ncbi.nlm.nih.gov/pubmed/16172261
http://dx.doi.org/10.1084/jem.20050665