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TLR9 regulates Th1 responses and cooperates with TLR2 in mediating optimal resistance to Mycobacterium tuberculosis

To investigate the role of Toll-like receptor (TLR)9 in the immune response to mycobacteria as well as its cooperation with TLR2, a receptor known to be triggered by several major mycobacterial ligands, we analyzed the resistance of TLR9(−/−) as well as TLR2/9 double knockout mice to aerosol infecti...

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Detalles Bibliográficos
Autores principales: Bafica, Andre, Scanga, Charles A., Feng, Carl G., Leifer, Cynthia, Cheever, Allen, Sher, Alan
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212963/
https://www.ncbi.nlm.nih.gov/pubmed/16365150
http://dx.doi.org/10.1084/jem.20051782