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TLR9 regulates Th1 responses and cooperates with TLR2 in mediating optimal resistance to Mycobacterium tuberculosis
To investigate the role of Toll-like receptor (TLR)9 in the immune response to mycobacteria as well as its cooperation with TLR2, a receptor known to be triggered by several major mycobacterial ligands, we analyzed the resistance of TLR9(−/−) as well as TLR2/9 double knockout mice to aerosol infecti...
Autores principales: | Bafica, Andre, Scanga, Charles A., Feng, Carl G., Leifer, Cynthia, Cheever, Allen, Sher, Alan |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212963/ https://www.ncbi.nlm.nih.gov/pubmed/16365150 http://dx.doi.org/10.1084/jem.20051782 |
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