Caspase-dependent immunogenicity of doxorubicin-induced tumor cell death

Systemic anticancer chemotherapy is immunosuppressive and mostly induces nonimmunogenic tumor cell death. Here, we show that even in the absence of any adjuvant, tumor cells dying in response to anthracyclins can elicit an effective antitumor immune response that suppresses the growth of inoculated...

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Detalles Bibliográficos
Autores principales: Casares, Noelia, Pequignot, Marie O., Tesniere, Antoine, Ghiringhelli, François, Roux, Stéphan, Chaput, Nathalie, Schmitt, Elise, Hamai, Ahmed, Hervas-Stubbs, Sandra, Obeid, Michel, Coutant, Frédéric, Métivier, Didier, Pichard, Evelyne, Aucouturier, Pierre, Pierron, Gérard, Garrido, Carmen, Zitvogel, Laurence, Kroemer, Guido
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212968/
https://www.ncbi.nlm.nih.gov/pubmed/16365148
http://dx.doi.org/10.1084/jem.20050915

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212968/
https://www.ncbi.nlm.nih.gov/pubmed/16365148
http://dx.doi.org/10.1084/jem.20050915

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