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BAFF regulates B cell survival by downregulating the BH3-only family member Bim via the ERK pathway
The B cell activating factor belonging to the tumor necrosis factor family (BAFF) is required for B cell survival and maturation. The mechanisms by which BAFF mediates B cell survival are less understood. We found that BAFF and a proliferation-inducing ligand (APRIL), which are related, block B cell...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212971/ https://www.ncbi.nlm.nih.gov/pubmed/16301744 http://dx.doi.org/10.1084/jem.20051283 |