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Sequential development of interleukin 2–dependent effector and regulatory T cells in response to endogenous systemic antigen
Transfer of naive antigen-specific CD4(+) T cells into lymphopenic mice that express an endogenous antigen as a systemic, secreted protein results in severe autoimmunity resembling graft-versus-host disease. T cells that respond to this endogenous antigen develop into effector cells that cause the d...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212975/ https://www.ncbi.nlm.nih.gov/pubmed/16287710 http://dx.doi.org/10.1084/jem.20050855 |