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Sequential development of interleukin 2–dependent effector and regulatory T cells in response to endogenous systemic antigen

Transfer of naive antigen-specific CD4(+) T cells into lymphopenic mice that express an endogenous antigen as a systemic, secreted protein results in severe autoimmunity resembling graft-versus-host disease. T cells that respond to this endogenous antigen develop into effector cells that cause the d...

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Detalles Bibliográficos
Autores principales:	Knoechel, Birgit, Lohr, Jens, Kahn, Estelle, Bluestone, Jeffrey A., Abbas, Abul K.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2005
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212975/ https://www.ncbi.nlm.nih.gov/pubmed/16287710 http://dx.doi.org/10.1084/jem.20050855

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