Coordinated oncogenic transformation and inhibition of host immune responses by the PAX3-FKHR fusion oncoprotein

Tumors have evolved elaborate mechanisms for evading immune detection, such as production of immunoinhibitory cytokines and down-regulation of major histocompatibility complex (MHC) expression. We have studied PAX3-FKHR as an example of an oncogenic fusion protein associated with an aggressive metas...

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Detalles Bibliográficos
Autores principales: Nabarro, Stephen, Himoudi, Nourredine, Papanastasiou, Antigoni, Gilmour, Kimberly, Gibson, Sian, Sebire, Neil, Thrasher, Adrian, Blundell, Michael P., Hubank, Mike, Canderan, Glenda, Anderson, John
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212991/
https://www.ncbi.nlm.nih.gov/pubmed/16287709
http://dx.doi.org/10.1084/jem.20050730

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212991/
https://www.ncbi.nlm.nih.gov/pubmed/16287709
http://dx.doi.org/10.1084/jem.20050730

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