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PKCβ regulates BCR-mediated IKK activation by facilitating the interaction between TAK1 and CARMA1

The B cell antigen receptor (BCR)–mediated activation of IκB kinase (IKK) and nuclear factor–κB require protein kinase C (PKC)β; however, the mechanism by which PKCβ regulates IKK is unclear. Here, we demonstrate that another protein kinase, TGFβ-activated kinase (TAK)1, is essential for IKK activat...

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Detalles Bibliográficos
Autores principales: Shinohara, Hisaaki, Yasuda, Tomoharu, Aiba, Yuichi, Sanjo, Hideki, Hamadate, Megumi, Watarai, Hiroshi, Sakurai, Hiroaki, Kurosaki, Tomohiro
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212994/
https://www.ncbi.nlm.nih.gov/pubmed/16301747
http://dx.doi.org/10.1084/jem.20051591