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Aberrant T cell differentiation in the absence of Dicer

Dicer is an RNaseIII-like enzyme that is required for generating short interfering RNAs and microRNAs. The latter have been implicated in regulating cell fate determination in invertebrates and vertebrates. To test the requirement for Dicer in cell-lineage decisions in a mammalian organism, we have...

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Detalles Bibliográficos
Autores principales: Muljo, Stefan A., Ansel, K. Mark, Kanellopoulou, Chryssa, Livingston, David M., Rao, Anjana, Rajewsky, Klaus
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212998/
https://www.ncbi.nlm.nih.gov/pubmed/16009718
http://dx.doi.org/10.1084/jem.20050678