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Structural basis for the function and regulation of the receptor protein tyrosine phosphatase CD45

CD45 is the prototypic member of transmembrane receptor-like protein tyrosine phosphatases (RPTPs) and has essential roles in immune functions. The cytoplasmic region of CD45, like many other RPTPs, contains two homologous protein tyrosine phosphatase domains, active domain 1 (D1) and catalytically...

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Detalles Bibliográficos
Autores principales: Nam, Hyun-Joo, Poy, Florence, Saito, Haruo, Frederick, Christin A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213029/
https://www.ncbi.nlm.nih.gov/pubmed/15684325
http://dx.doi.org/10.1084/jem.20041890