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Structural basis for the function and regulation of the receptor protein tyrosine phosphatase CD45
CD45 is the prototypic member of transmembrane receptor-like protein tyrosine phosphatases (RPTPs) and has essential roles in immune functions. The cytoplasmic region of CD45, like many other RPTPs, contains two homologous protein tyrosine phosphatase domains, active domain 1 (D1) and catalytically...
Autores principales: | Nam, Hyun-Joo, Poy, Florence, Saito, Haruo, Frederick, Christin A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213029/ https://www.ncbi.nlm.nih.gov/pubmed/15684325 http://dx.doi.org/10.1084/jem.20041890 |
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