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Anthrax toxins suppress T lymphocyte activation by disrupting antigen receptor signaling

Anthrax is an infection caused by pathogenic strains of Bacillus anthracis, which secretes a three-component toxic complex consisting of protective antigen (PA), edema factor (EF), and lethal factor (LF). PA forms binary complexes with either LF or EF and mediates their entry into host cells. Althou...

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Detalles Bibliográficos
Autores principales: Paccani, Silvia Rossi, Tonello, Fiorella, Ghittoni, Raffaella, Natale, Mariarita, Muraro, Lucia, D'Elios, Mario Milco, Tang, Wei-Jen, Montecucco, Cesare, Baldari, Cosima T.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213032/
https://www.ncbi.nlm.nih.gov/pubmed/15699068
http://dx.doi.org/10.1084/jem.20041557