Anti-CD63 antibodies suppress IgE-dependent allergic reactions in vitro and in vivo

High-affinity IgE receptor (FcɛRI) cross-linking on mast cells (MCs) induces secretion of preformed allergy mediators (degranulation) and synthesis of lipid mediators and cytokines. Degranulation produces many symptoms of immediate-type allergic reactions and is modulated by adhesion to surfaces coa...

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Detalles Bibliográficos
Autores principales: Kraft, Stefan, Fleming, Tony, Billingsley, James M., Lin, Shih-Yao, Jouvin, Marie-Hélène, Storz, Peter, Kinet, Jean-Pierre
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213034/
https://www.ncbi.nlm.nih.gov/pubmed/15684326
http://dx.doi.org/10.1084/jem.20042085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213034/
https://www.ncbi.nlm.nih.gov/pubmed/15684326
http://dx.doi.org/10.1084/jem.20042085

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