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Anti-CD63 antibodies suppress IgE-dependent allergic reactions in vitro and in vivo
High-affinity IgE receptor (FcɛRI) cross-linking on mast cells (MCs) induces secretion of preformed allergy mediators (degranulation) and synthesis of lipid mediators and cytokines. Degranulation produces many symptoms of immediate-type allergic reactions and is modulated by adhesion to surfaces coa...
Autores principales: | Kraft, Stefan, Fleming, Tony, Billingsley, James M., Lin, Shih-Yao, Jouvin, Marie-Hélène, Storz, Peter, Kinet, Jean-Pierre |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213034/ https://www.ncbi.nlm.nih.gov/pubmed/15684326 http://dx.doi.org/10.1084/jem.20042085 |
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