Cargando…

The adaptor molecules LAT and SLP-76 are specifically targeted by Yersinia to inhibit T cell activation

T cell responses are critical to the survival of Yersinia-infected animals. Yersinia have the ability to directly suppress T lymphocyte activation through the virulence factor YopH, a tyrosine phosphatase. Using single cell video microscopy and FACS analysis, here we show that even an average of one...

Descripción completa

Detalles Bibliográficos
Autores principales: Gerke, Christiane, Falkow, Stanley, Chien, Yueh-hsiu
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213036/
https://www.ncbi.nlm.nih.gov/pubmed/15699071
http://dx.doi.org/10.1084/jem.20041120