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The adaptor molecules LAT and SLP-76 are specifically targeted by Yersinia to inhibit T cell activation
T cell responses are critical to the survival of Yersinia-infected animals. Yersinia have the ability to directly suppress T lymphocyte activation through the virulence factor YopH, a tyrosine phosphatase. Using single cell video microscopy and FACS analysis, here we show that even an average of one...
Autores principales: | Gerke, Christiane, Falkow, Stanley, Chien, Yueh-hsiu |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213036/ https://www.ncbi.nlm.nih.gov/pubmed/15699071 http://dx.doi.org/10.1084/jem.20041120 |
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