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An orderly inactivation of intracellular retention signals controls surface expression of the T cell antigen receptor
Exit from the endoplasmic reticulum (ER) is an important checkpoint for proper assembly of multimeric plasma membrane receptors. The six subunits of the T cell receptor (TCR; TCRα, TCRβ, CD3γ, CD3δ, CD3ɛ, and CD3ζ) are each endowed with ER retention/retrieval signals, and regulation of its targeting...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213059/ https://www.ncbi.nlm.nih.gov/pubmed/15728236 http://dx.doi.org/10.1084/jem.20041133 |