The BCL2A1 gene as a pre–T cell receptor–induced regulator of thymocyte survival

The pre–T cell receptor (TCR) is expressed early during T cell development and imposes a tight selection for differentiating T cell progenitors. Pre-TCR–expressing cells are selected to survive and differentiate further, whereas pre-TCR(−) cells are “negatively” selected to die. The mechanisms of pr...

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Detalles Bibliográficos
Autores principales: Mandal, Malay, Borowski, Christine, Palomero, Teresa, Ferrando, Adolfo A., Oberdoerffer, Philipp, Meng, Fanyong, Ruiz-Vela, Antonio, Ciofani, Maria, Zuniga-Pflucker, Juan-Carlos, Screpanti, Isabella, Look, A. Thomas, Korsmeyer, Stanley J., Rajewsky, Klaus, von Boehmer, Harald, Aifantis, Iannis
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213063/
https://www.ncbi.nlm.nih.gov/pubmed/15728238
http://dx.doi.org/10.1084/jem.20041924

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213063/
https://www.ncbi.nlm.nih.gov/pubmed/15728238
http://dx.doi.org/10.1084/jem.20041924

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