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Mycobacterium tuberculosis controls host innate immune activation through cyclopropane modification of a glycolipid effector molecule

Mycobacterium tuberculosis (Mtb) infection remains a global health crisis. Recent genetic evidence implicates specific cell envelope lipids in Mtb pathogenesis, but it is unclear whether these cell envelope compounds affect pathogenesis through a structural role in the cell wall or as pathogenesis e...

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Detalles Bibliográficos
Autores principales: Rao, Vivek, Fujiwara, Nagatoshi, Porcelli, Steven A., Glickman, Michael S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213067/
https://www.ncbi.nlm.nih.gov/pubmed/15710652
http://dx.doi.org/10.1084/jem.20041668