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Balancing diversity and tolerance: lessons from patients with systemic lupus erythematosus

The autoimmune disease systemic lupus erythematosus (SLE) is caused by a failure of B cell tolerance. Recent studies in mouse models of SLE have identified several distinct tolerance checkpoints that must each function appropriately to protect against disease. However, studies of B cell repertoire s...

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Detalles Bibliográficos
Autores principales: Jacobi, Annett M., Diamond, Betty
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213089/
https://www.ncbi.nlm.nih.gov/pubmed/16061723
http://dx.doi.org/10.1084/jem.20050221