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Balancing diversity and tolerance: lessons from patients with systemic lupus erythematosus
The autoimmune disease systemic lupus erythematosus (SLE) is caused by a failure of B cell tolerance. Recent studies in mouse models of SLE have identified several distinct tolerance checkpoints that must each function appropriately to protect against disease. However, studies of B cell repertoire s...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213089/ https://www.ncbi.nlm.nih.gov/pubmed/16061723 http://dx.doi.org/10.1084/jem.20050221 |