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Vaccinia virus protein A46R targets multiple Toll-like–interleukin-1 receptor adaptors and contributes to virulence

Viral immune evasion strategies target key aspects of the host antiviral response. Recently, it has been recognized that Toll-like receptors (TLRs) have a role in innate defense against viruses. Here, we define the function of the vaccinia virus (VV) protein A46R and show it inhibits intracellular s...

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Detalles Bibliográficos
Autores principales: Stack, Julianne, Haga, Ismar R., Schröder, Martina, Bartlett, Nathan W., Maloney, Geraldine, Reading, Patrick C., Fitzgerald, Katherine A., Smith, Geoffrey L., Bowie, Andrew G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213104/
https://www.ncbi.nlm.nih.gov/pubmed/15767367
http://dx.doi.org/10.1084/jem.20041442