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Vaccinia virus protein A46R targets multiple Toll-like–interleukin-1 receptor adaptors and contributes to virulence
Viral immune evasion strategies target key aspects of the host antiviral response. Recently, it has been recognized that Toll-like receptors (TLRs) have a role in innate defense against viruses. Here, we define the function of the vaccinia virus (VV) protein A46R and show it inhibits intracellular s...
Autores principales: | Stack, Julianne, Haga, Ismar R., Schröder, Martina, Bartlett, Nathan W., Maloney, Geraldine, Reading, Patrick C., Fitzgerald, Katherine A., Smith, Geoffrey L., Bowie, Andrew G. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213104/ https://www.ncbi.nlm.nih.gov/pubmed/15767367 http://dx.doi.org/10.1084/jem.20041442 |
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