In vivo depletion of lung CD11c(+) dendritic cells during allergen challenge abrogates the characteristic features of asthma

Although dendritic cells (DCs) play an important role in sensitization to inhaled allergens, their function in ongoing T helper (Th)2 cell–mediated eosinophilic airway inflammation underlying bronchial asthma is currently unknown. Here, we show in an ovalbumin (OVA)-driven murine asthma model that a...

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Detalles Bibliográficos
Autores principales: van Rijt, Leonie S., Jung, Steffen, KleinJan, Alex, Vos, Nanda, Willart, Monique, Duez, Catherine, Hoogsteden, Henk C., Lambrecht, Bart N.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213109/
https://www.ncbi.nlm.nih.gov/pubmed/15781587
http://dx.doi.org/10.1084/jem.20042311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213109/
https://www.ncbi.nlm.nih.gov/pubmed/15781587
http://dx.doi.org/10.1084/jem.20042311

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