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In vivo depletion of lung CD11c(+) dendritic cells during allergen challenge abrogates the characteristic features of asthma
Although dendritic cells (DCs) play an important role in sensitization to inhaled allergens, their function in ongoing T helper (Th)2 cell–mediated eosinophilic airway inflammation underlying bronchial asthma is currently unknown. Here, we show in an ovalbumin (OVA)-driven murine asthma model that a...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213109/ https://www.ncbi.nlm.nih.gov/pubmed/15781587 http://dx.doi.org/10.1084/jem.20042311 |