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VEGF-A induces tumor and sentinel lymph node lymphangiogenesis and promotes lymphatic metastasis

The mechanisms of tumor metastasis to the sentinel lymph nodes are poorly understood. Vascular endothelial growth factor (VEGF)-A plays a principle role in tumor progression and angiogenesis; however, its role in tumor-associated lymphangiogenesis and lymphatic metastasis has remained unclear. We cr...

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Detalles Bibliográficos
Autores principales: Hirakawa, Satoshi, Kodama, Shohta, Kunstfeld, Rainer, Kajiya, Kentaro, Brown, Lawrence F., Detmar, Michael
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213132/
https://www.ncbi.nlm.nih.gov/pubmed/15809353
http://dx.doi.org/10.1084/jem.20041896