Repeated stimulation of CD4 effector T cells can limit their protective function

Chronic infections often result in CD8 T-cell deletion or functional nonresponsiveness. However, to date no definitive studies have attempted to determine the impact of repeated T cell receptor stimulation on CD4 effector T cell generation. We have determined that when antigen presentation is limite...

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Detalles Bibliográficos
Autores principales: Jelley-Gibbs, Dawn M., Dibble, John P., Filipson, Svetlana, Haynes, Laura, Kemp, Roslyn A., Swain, Susan L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213138/
https://www.ncbi.nlm.nih.gov/pubmed/15795235
http://dx.doi.org/10.1084/jem.20041852

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213138/
https://www.ncbi.nlm.nih.gov/pubmed/15795235
http://dx.doi.org/10.1084/jem.20041852

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