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Single cell analysis shows decreasing FoxP3 and TGFβ1 coexpressing CD4(+)CD25(+) regulatory T cells during autoimmune diabetes

Natural CD4(+)CD25(+) regulatory T (CD4(+)CD25(+) T reg) cells play a key role in the immunoregulation of autoimmunity. However, little is known about the interactions between CD4(+)CD25(+) T reg cells and autoreactive T cells. This is due, in part, to the difficulty of using cell surface markers to...

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Detalles Bibliográficos
Autores principales: Pop, Shannon M., Wong, Carmen P., Culton, Donna A., Clarke, Stephen H., Tisch, Roland
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213147/
https://www.ncbi.nlm.nih.gov/pubmed/15837817
http://dx.doi.org/10.1084/jem.20042398