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Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator–activated receptor-γ

5-aminosalicylic acid (5-ASA) is an antiinflammatory drug widely used in the treatment of inflammatory bowel diseases. It is known to inhibit the production of cytokines and inflammatory mediators, but the mechanism underlying the intestinal effects of 5-ASA remains unknown. Based on the common acti...

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Detalles Bibliográficos
Autores principales: Rousseaux, Christel, Lefebvre, Bruno, Dubuquoy, Laurent, Lefebvre, Philippe, Romano, Olivier, Auwerx, Johan, Metzger, Daniel, Wahli, Walter, Desvergne, Béatrice, Naccari, Gian Carlo, Chavatte, Philippe, Farce, Amaury, Bulois, Philippe, Cortot, Antoine, Colombel, Jean Frédéric, Desreumaux, Pierre
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213148/
https://www.ncbi.nlm.nih.gov/pubmed/15824083
http://dx.doi.org/10.1084/jem.20041948