Cargando…
Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator–activated receptor-γ
5-aminosalicylic acid (5-ASA) is an antiinflammatory drug widely used in the treatment of inflammatory bowel diseases. It is known to inhibit the production of cytokines and inflammatory mediators, but the mechanism underlying the intestinal effects of 5-ASA remains unknown. Based on the common acti...
Autores principales: | Rousseaux, Christel, Lefebvre, Bruno, Dubuquoy, Laurent, Lefebvre, Philippe, Romano, Olivier, Auwerx, Johan, Metzger, Daniel, Wahli, Walter, Desvergne, Béatrice, Naccari, Gian Carlo, Chavatte, Philippe, Farce, Amaury, Bulois, Philippe, Cortot, Antoine, Colombel, Jean Frédéric, Desreumaux, Pierre |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213148/ https://www.ncbi.nlm.nih.gov/pubmed/15824083 http://dx.doi.org/10.1084/jem.20041948 |
Ejemplares similares
-
The 5-aminosalicylic acid antineoplastic effect in the intestine is mediated by PPARγ
por: Rousseaux, Christel, et al.
Publicado: (2013) -
GED-0507 attenuates lung fibrosis by counteracting myofibroblast transdifferentiation in vivo and in vitro
por: Speca, Silvia, et al.
Publicado: (2021) -
Attenuation of Colon Inflammation through Activators of the Retinoid X Receptor (Rxr)/Peroxisome Proliferator–Activated Receptor γ (Pparγ) Heterodimer: A Basis for New Therapeutic Strategies
por: Desreumaux, Pierre, et al.
Publicado: (2001) -
Peroxisome proliferator‐activated receptor gamma (PPARγ) regulates lactase expression and activity in the gut
por: Fumery, Mathurin, et al.
Publicado: (2017) -
Relationships between Th1 or Th2 iNKT Cell Activity and Structures of CD1d-Antigen Complexes: Meta-analysis of CD1d-Glycolipids Dynamics Simulations
por: Laurent, Xavier, et al.
Publicado: (2014)