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Developmental regulation of Foxp3 expression during ontogeny

Thymectomy of neonatal mice can result in the development of autoimmune pathology. It has been proposed that thymic output of regulatory T (T reg) cells is delayed during ontogeny and that the development of autoimmune disease in neonatally thymectomized mice is caused by the escape of self-reactive...

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Detalles Bibliográficos
Autores principales: Fontenot, Jason D., Dooley, James L., Farr, Andrew G., Rudensky, Alexander Y.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213175/
https://www.ncbi.nlm.nih.gov/pubmed/16203863
http://dx.doi.org/10.1084/jem.20050784