The human macrophage mannose receptor directs Mycobacterium tuberculosis lipoarabinomannan-mediated phagosome biogenesis

Mycobacterium tuberculosis (M.tb) survives in macrophages in part by limiting phagosome–lysosome (P-L) fusion. M.tb mannose-capped lipoarabinomannan (ManLAM) blocks phagosome maturation. The pattern recognition mannose receptor (MR) binds to the ManLAM mannose caps and mediates phagocytosis of bacil...

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Detalles Bibliográficos
Autores principales: Kang, Peter B., Azad, Abul K., Torrelles, Jordi B., Kaufman, Thomas M., Beharka, Alison, Tibesar, Eric, DesJardin, Lucy E., Schlesinger, Larry S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213176/
https://www.ncbi.nlm.nih.gov/pubmed/16203868
http://dx.doi.org/10.1084/jem.20051239

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213176/
https://www.ncbi.nlm.nih.gov/pubmed/16203868
http://dx.doi.org/10.1084/jem.20051239

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