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Role of interleukin-1 (IL-1) in the pathogenesis of systemic onset juvenile idiopathic arthritis and clinical response to IL-1 blockade

Systemic onset juvenile idiopathic arthritis (SoJIA) encompasses ∼10% of cases of arthritis that begin in childhood. The disease is unique in terms of clinical manifestations, severity of joint involvement, and lack of response to tumor necrosis factor blockade. Here, we show that serum from SoJIA p...

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Detalles Bibliográficos
Autores principales: Pascual, Virginia, Allantaz, Florence, Arce, Edsel, Punaro, Marilynn, Banchereau, Jacques
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213182/
https://www.ncbi.nlm.nih.gov/pubmed/15851489
http://dx.doi.org/10.1084/jem.20050473