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The 3′ end of the heavy chain constant region locus enhances germline transcription and switch recombination of the four γ genes
The switch in immunoglobulin (Ig) heavy chain class is preceded by germline transcription and then mediated by a DNA recombination event. To study germline transcription and class switch recombination we used transgenic mice with a 230-kilobase bacterial artificial chromosome that included a rearran...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213191/ https://www.ncbi.nlm.nih.gov/pubmed/15851486 http://dx.doi.org/10.1084/jem.20041988 |