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Innate immunity against Francisella tularensis is dependent on the ASC/caspase-1 axis

Francisella tularensis is a highly infectious gram-negative coccobacillus that causes the zoonosis tularemia. This bacterial pathogen causes a plague-like disease in humans after exposure to as few as 10 cells. Many of the mechanisms by which the innate immune system fights Francisella are unknown....

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Detalles Bibliográficos
Autores principales: Mariathasan, Sanjeev, Weiss, David S., Dixit, Vishva M., Monack, Denise M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213215/
https://www.ncbi.nlm.nih.gov/pubmed/16230474
http://dx.doi.org/10.1084/jem.20050977