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Endogenous human cytomegalovirus gB is presented efficiently by MHC class II molecules to CD4(+) CTL

Human cytomegalovirus (HCMV) infects endothelial, epithelial, and glial cells in vivo. These cells can express MHC class II proteins, but are unlikely to play important roles in priming host immunity. Instead, it seems that class II presentation of endogenous HCMV antigens in these cells allows reco...

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Detalles Bibliográficos
Autores principales: Hegde, Nagendra R., Dunn, Claire, Lewinsohn, David M., Jarvis, Michael A., Nelson, Jay A., Johnson, David C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213219/
https://www.ncbi.nlm.nih.gov/pubmed/16216889
http://dx.doi.org/10.1084/jem.20050162