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Endogenous human cytomegalovirus gB is presented efficiently by MHC class II molecules to CD4(+) CTL
Human cytomegalovirus (HCMV) infects endothelial, epithelial, and glial cells in vivo. These cells can express MHC class II proteins, but are unlikely to play important roles in priming host immunity. Instead, it seems that class II presentation of endogenous HCMV antigens in these cells allows reco...
Autores principales: | Hegde, Nagendra R., Dunn, Claire, Lewinsohn, David M., Jarvis, Michael A., Nelson, Jay A., Johnson, David C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213219/ https://www.ncbi.nlm.nih.gov/pubmed/16216889 http://dx.doi.org/10.1084/jem.20050162 |
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