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Protection from Alzheimer's-like disease in the mouse by genetic ablation of inducible nitric oxide synthase

Brains from subjects who have Alzheimer's disease (AD) express inducible nitric oxide synthase (iNOS). We tested the hypothesis that iNOS contributes to AD pathogenesis. Immunoreactive iNOS was detected in brains of mice with AD-like disease resulting from transgenic expression of mutant human...

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Detalles Bibliográficos
Autores principales: Nathan, Carl, Calingasan, Noel, Nezezon, Jon, Ding, Aihao, Lucia, M. Scott, La Perle, Krista, Fuortes, Michele, Lin, Michael, Ehrt, Sabine, Kwon, Nyoun Soo, Chen, Junyu, Vodovotz, Yoram, Kipiani, Khatuna, Beal, M. Flint
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213235/
https://www.ncbi.nlm.nih.gov/pubmed/16260491
http://dx.doi.org/10.1084/jem.20051529